D34E (p.Asp34Glu) variant of XRCC3 (DNA repair protein XRCC3)
D34E (p.Asp34Glu) in XRCC3 (DNA repair protein XRCC3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
D34E (p.Asp34Glu) variant details
- p.Asp34Glu
- ExAC rs757649541
- TOPMed rs757649541
- gnomAD rs757649541
- Missense
- Variant Prioritization Score for Impact Estimate 0.134
- REVEL 0.10
- CADD 7.26
- PolyPhen-2 0.13
- SIFT 0.21
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available