D2Y (p.Asp2Tyr) variant of XRCC3 (DNA repair protein XRCC3)
D2Y (p.Asp2Tyr) in XRCC3 (DNA repair protein XRCC3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
D2Y (p.Asp2Tyr) variant details
- p.Asp2Tyr
- cosmic curated COSV10457
- Missense
- Variant Prioritization Score for Impact Estimate 0.461
- REVEL 0.33
- CADD 24.20
- PolyPhen-2 0.92
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.3e-05)
- Structural context available