C86Y (p.Cys86Tyr) variant of XRCC3 (DNA repair protein XRCC3)
C86Y (p.Cys86Tyr) in XRCC3 (DNA repair protein XRCC3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data and structural context.
C86Y (p.Cys86Tyr) variant details
- p.Cys86Tyr
- TOPMed rs953627555
- Missense
- Variant Prioritization Score for Impact Estimate 0.56
- REVEL 0.53
- CADD 25.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 6.3e-05)
- Structural context available