C141F (p.Cys141Phe) variant of XRCC3 (DNA repair protein XRCC3)
C141F (p.Cys141Phe) in XRCC3 (DNA repair protein XRCC3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data and structural context.
C141F (p.Cys141Phe) variant details
- p.Cys141Phe
- Ensembl rs2151931512
- Missense
- Variant Prioritization Score for Impact Estimate 0.561
- REVEL 0.43
- CADD 23.30
- PolyPhen-2 0.14
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available