A137S (p.Ala137Ser) variant of XRCC3 (DNA repair protein XRCC3)
A137S (p.Ala137Ser) in XRCC3 (DNA repair protein XRCC3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
A137S (p.Ala137Ser) variant details
- p.Ala137Ser
- Ensembl rs1595656245
- Missense
- Variant Prioritization Score for Impact Estimate 0.432
- REVEL 0.33
- CADD 22.50
- PolyPhen-2 0.40
- SIFT 0.01
- Most common in the East Asian population (allele frequency 2.8e-05)
- Structural context available