A137P (p.Ala137Pro) variant of XRCC3 (DNA repair protein XRCC3)
A137P (p.Ala137Pro) in XRCC3 (DNA repair protein XRCC3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
A137P (p.Ala137Pro) variant details
- p.Ala137Pro
- Ensembl rs1595656245
- Missense
- Variant Prioritization Score for Impact Estimate 0.574
- REVEL 0.56
- CADD 24.10
- PolyPhen-2 0.92
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3.1e-05)
- Structural context available