A123P (p.Ala123Pro) variant of XRCC3 (DNA repair protein XRCC3)
A123P (p.Ala123Pro) in XRCC3 (DNA repair protein XRCC3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
A123P (p.Ala123Pro) variant details
- p.Ala123Pro
- ExAC rs777779663
- TOPMed rs777779663
- gnomAD rs777779663
- Missense
- Variant Prioritization Score for Impact Estimate 0.353
- REVEL 0.27
- CADD 22.80
- PolyPhen-2 0.64
- SIFT 0.03
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available