A106T (p.Ala106Thr) variant of XRCC3 (DNA repair protein XRCC3)
A106T (p.Ala106Thr) in XRCC3 (DNA repair protein XRCC3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
A106T (p.Ala106Thr) variant details
- p.Ala106Thr
- TOPMed rs1486507903
- gnomAD rs1486507903
- Missense
- Variant Prioritization Score for Impact Estimate 0.388
- REVEL 0.20
- CADD 22.70
- PolyPhen-2 0.76
- SIFT 0.07
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available