p.Cys2 Ala4del variant of XRCC2 (DNA repair protein XRCC2)

Name: XRCC2 p.Cys2 Ala4del variant | CATVariant
Creator: Center for Precision Medicine and Data Sciences
Published: 2026-08-20
License: https://catvariant.com/terms-of-use

p.Cys2 Ala4del in XRCC2 (DNA repair protein XRCC2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.

p.Cys2 Ala4del variant details

gnomAD 7-152676066-AAGGC
Inframe Deletion
Variant Prioritization Score for Impact Estimate 0.343
CADD 20.50
Most common in the Non-Finnish European population (allele frequency 9e-07)
Structural context available
Literature evidence available