S3T (p.Ser3Thr) variant of XRCC2 (DNA repair protein XRCC2)
S3T (p.Ser3Thr) in XRCC2 (DNA repair protein XRCC2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
S3T (p.Ser3Thr) variant details
- p.Ser3Thr
- gnomAD 7-152676072-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.201
- REVEL 0.05
- MetaLR 0.13
- MetaSVM -0.89
- CADD 20.90
- PolyPhen-2 0.03
- SIFT 0.13
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available