S3N (p.Ser3Asn) variant of XRCC2 (DNA repair protein XRCC2)
S3N (p.Ser3Asn) in XRCC2 (DNA repair protein XRCC2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
S3N (p.Ser3Asn) variant details
- p.Ser3Asn
- ExAC rs775671215
- Missense
- Variant Prioritization Score for Impact Estimate 0.207
- REVEL 0.06
- MetaLR 0.13
- MetaSVM -0.89
- CADD 21.60
- PolyPhen-2 0.03
- SIFT 0.26
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available