S37L (p.Ser37Leu) variant of XRCC2 (DNA repair protein XRCC2)
S37L (p.Ser37Leu) in XRCC2 (DNA repair protein XRCC2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
S37L (p.Ser37Leu) variant details
- p.Ser37Leu
- Ensembl rs2116999532
- Missense
- Variant Prioritization Score for Impact Estimate 0.273
- REVEL 0.13
- MetaLR 0.14
- MetaSVM -0.80
- CADD 21.60
- PolyPhen-2 0.05
- SIFT 0.11
- Population evidence available
- Structural context available