S37F (p.Ser37Phe) variant of XRCC2 (DNA repair protein XRCC2)
S37F (p.Ser37Phe) in XRCC2 (DNA repair protein XRCC2) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data, published literature, and structural context.
S37F (p.Ser37Phe) variant details
- p.Ser37Phe
- rs1213272601
- gnomAD 7-152660712-G-GA
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.551
- CADD 28.20
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available
- Literature evidence available