S23F (p.Ser23Phe) variant of XRCC2 (DNA repair protein XRCC2)
S23F (p.Ser23Phe) in XRCC2 (DNA repair protein XRCC2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
S23F (p.Ser23Phe) variant details
- p.Ser23Phe
- gnomAD rs1388202730
- Missense
- Variant Prioritization Score for Impact Estimate 0.451
- REVEL 0.26
- MetaLR 0.32
- MetaSVM -0.40
- CADD 26.50
- PolyPhen-2 0.90
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available