P38R (p.Pro38Arg) variant of XRCC2 (DNA repair protein XRCC2)
P38R (p.Pro38Arg) in XRCC2 (DNA repair protein XRCC2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
P38R (p.Pro38Arg) variant details
- p.Pro38Arg
- gnomAD 7-152660709-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.387
- REVEL 0.22
- MetaLR 0.23
- MetaSVM -0.63
- CADD 26.20
- PolyPhen-2 0.58
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available