P29R (p.Pro29Arg) variant of XRCC2 (DNA repair protein XRCC2)
P29R (p.Pro29Arg) in XRCC2 (DNA repair protein XRCC2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
P29R (p.Pro29Arg) variant details
- p.Pro29Arg
- gnomAD 7-152660736-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.463
- REVEL 0.30
- MetaLR 0.28
- MetaSVM -0.64
- CADD 25.20
- PolyPhen-2 0.82
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available