M57V (p.Met57Val) variant of XRCC2 (DNA repair protein XRCC2)
M57V (p.Met57Val) in XRCC2 (DNA repair protein XRCC2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
M57V (p.Met57Val) variant details
- p.Met57Val
- gnomAD rs2098027527
- Missense
- Variant Prioritization Score for Impact Estimate 0.312
- REVEL 0.18
- MetaLR 0.26
- MetaSVM -0.67
- CADD 23.00
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available