K25* (p.Lys25Ter) variant of XRCC2 (DNA repair protein XRCC2)
K25* (p.Lys25Ter) in XRCC2 (DNA repair protein XRCC2) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data, published literature, and structural context.
K25* (p.Lys25Ter) variant details
- p.Lys25Ter
- gnomAD 7-152660749-T-A
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.632
- CADD 40.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available
- Literature evidence available