G41A (p.Gly41Ala) variant of XRCC2 (DNA repair protein XRCC2)
G41A (p.Gly41Ala) in XRCC2 (DNA repair protein XRCC2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.79 / 1. The record also includes population frequency data, published literature, and structural context.
G41A (p.Gly41Ala) variant details
- p.Gly41Ala
- gnomAD 7-152649363-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.792
- REVEL 0.78
- MetaLR 0.70
- MetaSVM 0.56
- CADD 33.00
- PolyPhen-2 1.00
- SIFT 0.21
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available
- Literature evidence available