E19G (p.Glu19Gly) variant of XRCC2 (DNA repair protein XRCC2)
E19G (p.Glu19Gly) in XRCC2 (DNA repair protein XRCC2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
E19G (p.Glu19Gly) variant details
- p.Glu19Gly
- gnomAD 7-152660766-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.278
- REVEL 0.14
- MetaLR 0.14
- MetaSVM -0.97
- CADD 22.70
- PolyPhen-2 0.02
- SIFT 0.25
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available
- Literature evidence available