D42G (p.Asp42Gly) variant of XRCC2 (DNA repair protein XRCC2)
D42G (p.Asp42Gly) in XRCC2 (DNA repair protein XRCC2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
D42G (p.Asp42Gly) variant details
- p.Asp42Gly
- gnomAD 7-152649360-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.269
- REVEL 0.21
- MetaLR 0.19
- MetaSVM -0.89
- CADD 22.70
- PolyPhen-2 0.05
- SIFT 0.71
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available
- Literature evidence available