D36G (p.Asp36Gly) variant of XRCC2 (DNA repair protein XRCC2)
D36G (p.Asp36Gly) in XRCC2 (DNA repair protein XRCC2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
D36G (p.Asp36Gly) variant details
- p.Asp36Gly
- gnomAD 7-152660715-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.223
- REVEL 0.07
- MetaLR 0.04
- MetaSVM -1.02
- CADD 21.90
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available