D34V (p.Asp34Val) variant of XRCC2 (DNA repair protein XRCC2)
D34V (p.Asp34Val) in XRCC2 (DNA repair protein XRCC2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
D34V (p.Asp34Val) variant details
- p.Asp34Val
- ExAC rs768885888
- gnomAD rs768885888
- Missense
- Variant Prioritization Score for Impact Estimate 0.281
- REVEL 0.13
- MetaLR 0.16
- MetaSVM -0.92
- CADD 22.90
- PolyPhen-2 0.04
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available