C2R (p.Cys2Arg) variant of XRCC2 (DNA repair protein XRCC2)
C2R (p.Cys2Arg) in XRCC2 (DNA repair protein XRCC2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
C2R (p.Cys2Arg) variant details
- p.Cys2Arg
- TOPMed rs2098040963
- gnomAD rs2098040963
- Missense
- Variant Prioritization Score for Impact Estimate 0.181
- REVEL 0.04
- MetaLR 0.11
- MetaSVM -1.00
- CADD 23.20
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available