G65R (p.Gly65Arg) variant of XPC (Q01831)
G65R (p.Gly65Arg) in XPC (Q01831) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
G65R (p.Gly65Arg) variant details
- p.Gly65Arg
- gnomAD rs1413843191
- Missense
- Variant Prioritization Score for Impact Estimate 0.109
- REVEL 0.06
- CADD 6.45
- PolyPhen-2 0.00
- SIFT 0.19
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available