G59V (p.Gly59Val) variant of XPC (Q01831)
G59V (p.Gly59Val) in XPC (Q01831) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
G59V (p.Gly59Val) variant details
- p.Gly59Val
- ExAC rs774670281
- gnomAD rs774670281
- Missense
- Variant Prioritization Score for Impact Estimate 0.133
- REVEL 0.06
- CADD 12.40
- PolyPhen-2 0.31
- SIFT 0.01
- Most common in the South Asian population (allele frequency 8.1e-05)
- Structural context available