F37C (p.Phe37Cys) variant of XPC (Q01831)
F37C (p.Phe37Cys) in XPC (Q01831) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
F37C (p.Phe37Cys) variant details
- p.Phe37Cys
- ExAC rs747594023
- TOPMed rs747594023
- gnomAD rs747594023
- Missense
- Variant Prioritization Score for Impact Estimate 0.159
- REVEL 0.13
- CADD 19.30
- PolyPhen-2 0.00
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available