R25L (p.Arg25Leu) variant of XPA (P23025)
R25L (p.Arg25Leu) in XPA (P23025) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
R25L (p.Arg25Leu) variant details
- p.Arg25Leu
- TOPMed rs1033405989
- gnomAD rs1033405989
- Missense
- Variant Prioritization Score for Impact Estimate 0.379
- REVEL 0.19
- CADD 24.10
- PolyPhen-2 0.07
- SIFT 0.09
- Most common in the HGDP:MANDENKA population (allele frequency 0.025)
- Structural context available