M98L (p.Met98Leu) variant of XPA (P23025)
M98L (p.Met98Leu) in XPA (P23025) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
M98L (p.Met98Leu) variant details
- p.Met98Leu
- TOPMed rs1339290732
- Missense
- Variant Prioritization Score for Impact Estimate 0.275
- REVEL 0.18
- CADD 16.30
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available