Y97H (p.Tyr97His) variant of XIAP (E3 ubiquitin-protein ligase XIAP)
Y97H (p.Tyr97His) in XIAP (E3 ubiquitin-protein ligase XIAP) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
Y97H (p.Tyr97His) variant details
- p.Tyr97His
- gnomAD rs1175389780
- Missense
- Variant Prioritization Score for Impact Estimate 0.155
- REVEL 0.04
- CADD 16.40
- PolyPhen-2 0.00
- SIFT 0.46
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available