Y97F (p.Tyr97Phe) variant of XIAP (E3 ubiquitin-protein ligase XIAP)
Y97F (p.Tyr97Phe) in XIAP (E3 ubiquitin-protein ligase XIAP) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
Y97F (p.Tyr97Phe) variant details
- p.Tyr97Phe
- gnomAD X-123885952-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.21
- REVEL 0.09
- CADD 17.70
- PolyPhen-2 0.33
- SIFT 0.67
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available
- Literature evidence available