T32P (p.Thr32Pro) variant of XIAP (E3 ubiquitin-protein ligase XIAP)
T32P (p.Thr32Pro) in XIAP (E3 ubiquitin-protein ligase XIAP) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data, published literature, and structural context.
T32P (p.Thr32Pro) variant details
- p.Thr32Pro
- gnomAD X-123885756-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.69
- REVEL 0.84
- CADD 25.00
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available
- Literature evidence available