T11S (p.Thr11Ser) variant of XIAP (E3 ubiquitin-protein ligase XIAP)
T11S (p.Thr11Ser) in XIAP (E3 ubiquitin-protein ligase XIAP) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
T11S (p.Thr11Ser) variant details
- p.Thr11Ser
- ExAC rs748327341
- gnomAD rs748327341
- Missense
- Variant Prioritization Score for Impact Estimate 0.25
- REVEL 0.09
- CADD 17.10
- PolyPhen-2 0.00
- SIFT 0.13
- Most common in the East Asian population (allele frequency 3.3e-05)
- Structural context available