S105C (p.Ser105Cys) variant of XIAP (E3 ubiquitin-protein ligase XIAP)
S105C (p.Ser105Cys) in XIAP (E3 ubiquitin-protein ligase XIAP) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
S105C (p.Ser105Cys) variant details
- p.Ser105Cys
- gnomAD X-123885976-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.252
- REVEL 0.03
- CADD 19.30
- PolyPhen-2 0.11
- SIFT 0.10
- Population evidence available
- Structural context available
- Literature evidence available