P14T (p.Pro14Thr) variant of XIAP (E3 ubiquitin-protein ligase XIAP)
P14T (p.Pro14Thr) in XIAP (E3 ubiquitin-protein ligase XIAP) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
P14T (p.Pro14Thr) variant details
- p.Pro14Thr
- Ensembl rs2148089294
- Missense
- Variant Prioritization Score for Impact Estimate 0.257
- REVEL 0.08
- CADD 13.80
- PolyPhen-2 0.01
- SIFT 0.60
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available