N89H (p.Asn89His) variant of XIAP (E3 ubiquitin-protein ligase XIAP)
N89H (p.Asn89His) in XIAP (E3 ubiquitin-protein ligase XIAP) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
N89H (p.Asn89His) variant details
- p.Asn89His
- ESP rs142087897
- TOPMed rs142087897
- Missense
- Variant Prioritization Score for Impact Estimate 0.452
- REVEL 0.37
- CADD 24.10
- PolyPhen-2 0.75
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 2.2e-05)
- Structural context available