N89D (p.Asn89Asp) variant of XIAP (E3 ubiquitin-protein ligase XIAP)
N89D (p.Asn89Asp) in XIAP (E3 ubiquitin-protein ligase XIAP) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
N89D (p.Asn89Asp) variant details
- p.Asn89Asp
- gnomAD X-123885927-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.335
- REVEL 0.20
- CADD 21.00
- PolyPhen-2 0.01
- SIFT 0.10
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available
- Literature evidence available