N112S (p.Asn112Ser) variant of XIAP (E3 ubiquitin-protein ligase XIAP)
N112S (p.Asn112Ser) in XIAP (E3 ubiquitin-protein ligase XIAP) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
N112S (p.Asn112Ser) variant details
- p.Asn112Ser
- cosmic curated COSV10084
- Missense
- Variant Prioritization Score for Impact Estimate 0.152
- REVEL 0.06
- CADD 17.40
- PolyPhen-2 0.02
- SIFT 0.14
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available