K85N (p.Lys85Asn) variant of XIAP (E3 ubiquitin-protein ligase XIAP)
K85N (p.Lys85Asn) in XIAP (E3 ubiquitin-protein ligase XIAP) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
K85N (p.Lys85Asn) variant details
- p.Lys85Asn
- ExAC rs758511888
- gnomAD rs758511888
- Missense
- Variant Prioritization Score for Impact Estimate 0.304
- REVEL 0.16
- CADD 17.90
- PolyPhen-2 0.01
- SIFT 0.27
- Most common in the Latino/Admixed American population (allele frequency 5.7e-05)
- Structural context available