K19M (p.Lys19Met) variant of XIAP (E3 ubiquitin-protein ligase XIAP)
K19M (p.Lys19Met) in XIAP (E3 ubiquitin-protein ligase XIAP) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
K19M (p.Lys19Met) variant details
- p.Lys19Met
- Ensembl rs2053344810
- Missense
- Variant Prioritization Score for Impact Estimate 0.308
- REVEL 0.15
- CADD 19.10
- PolyPhen-2 0.33
- SIFT 0.22
- Most common in the South Asian population (allele frequency 1.9e-05)
- Structural context available