G95D (p.Gly95Asp) variant of XIAP (E3 ubiquitin-protein ligase XIAP)
G95D (p.Gly95Asp) in XIAP (E3 ubiquitin-protein ligase XIAP) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
G95D (p.Gly95Asp) variant details
- p.Gly95Asp
- gnomAD X-123885946-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.3
- REVEL 0.16
- CADD 20.30
- PolyPhen-2 0.11
- SIFT 0.20
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available
- Literature evidence available