G81R (p.Gly81Arg) variant of XIAP (E3 ubiquitin-protein ligase XIAP)
G81R (p.Gly81Arg) in XIAP (E3 ubiquitin-protein ligase XIAP) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data, published literature, and structural context.
G81R (p.Gly81Arg) variant details
- p.Gly81Arg
- gnomAD X-123885903-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.492
- REVEL 0.33
- CADD 26.00
- PolyPhen-2 0.98
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available