G109D (p.Gly109Asp) variant of XIAP (E3 ubiquitin-protein ligase XIAP)
G109D (p.Gly109Asp) in XIAP (E3 ubiquitin-protein ligase XIAP) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
G109D (p.Gly109Asp) variant details
- p.Gly109Asp
- gnomAD X-123885988-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.174
- REVEL 0.04
- CADD 13.50
- PolyPhen-2 0.30
- SIFT 0.34
- Population evidence available
- Structural context available
- Literature evidence available