E20G (p.Glu20Gly) variant of XIAP (E3 ubiquitin-protein ligase XIAP)
E20G (p.Glu20Gly) in XIAP (E3 ubiquitin-protein ligase XIAP) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
E20G (p.Glu20Gly) variant details
- p.Glu20Gly
- gnomAD rs1419364869
- Missense
- Variant Prioritization Score for Impact Estimate 0.271
- REVEL 0.08
- CADD 22.50
- PolyPhen-2 0.00
- SIFT 0.07
- Most common in the East Asian population (allele frequency 3.3e-05)
- Structural context available