D77N (p.Asp77Asn) variant of XIAP (E3 ubiquitin-protein ligase XIAP)
D77N (p.Asp77Asn) in XIAP (E3 ubiquitin-protein ligase XIAP) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data and structural context.
D77N (p.Asp77Asn) variant details
- p.Asp77Asn
- TOPMed rs954289858
- Missense
- Variant Prioritization Score for Impact Estimate 0.738
- REVEL 0.76
- CADD 27.00
- Most common in the Non-Finnish European population (allele frequency 1.9e-05)
- Structural context available