C63Y (p.Cys63Tyr) variant of XIAP (E3 ubiquitin-protein ligase XIAP)
C63Y (p.Cys63Tyr) in XIAP (E3 ubiquitin-protein ligase XIAP) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.87 / 1. The record also includes population frequency data, published literature, and structural context.
C63Y (p.Cys63Tyr) variant details
- p.Cys63Tyr
- gnomAD X-123885850-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.87
- REVEL 0.98
- CADD 26.30
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available