V85L (p.Val85Leu) variant of WWTR1 (Q9GZV5)
V85L (p.Val85Leu) in WWTR1 (Q9GZV5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
V85L (p.Val85Leu) variant details
- p.Val85Leu
- TOPMed rs1197717753
- gnomAD rs1197717753
- Missense
- Variant Prioritization Score for Impact Estimate 0.3
- REVEL 0.07
- CADD 23.40
- PolyPhen-2 0.08
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available