T137I (p.Thr137Ile) variant of WWTR1 (Q9GZV5)
T137I (p.Thr137Ile) in WWTR1 (Q9GZV5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
T137I (p.Thr137Ile) variant details
- p.Thr137Ile
- cosmic curated COSV10525
- Missense
- Variant Prioritization Score for Impact Estimate 0.596
- REVEL 0.55
- CADD 27.00
- PolyPhen-2 0.85
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available