T135M (p.Thr135Met) variant of WWTR1 (Q9GZV5)
T135M (p.Thr135Met) in WWTR1 (Q9GZV5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.84 / 1. The record also includes population frequency data and structural context.
T135M (p.Thr135Met) variant details
- p.Thr135Met
- ExAC rs762322089
- gnomAD rs762322089
- Missense
- Variant Prioritization Score for Impact Estimate 0.839
- REVEL 0.93
- CADD 32.00
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 3.7e-06)
- Structural context available