T133I (p.Thr133Ile) variant of WWTR1 (Q9GZV5)
T133I (p.Thr133Ile) in WWTR1 (Q9GZV5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
T133I (p.Thr133Ile) variant details
- p.Thr133Ile
- gnomAD rs1231267072
- Missense
- Variant Prioritization Score for Impact Estimate 0.549
- REVEL 0.43
- CADD 25.50
- PolyPhen-2 0.08
- SIFT 0.00
- Most common in the Ashkenazi Jewish population (allele frequency 4.5e-05)
- Structural context available